As the use of GLP-1 receptor agonists like Ozempic and Wegovy continues to rise for diabetes management and weight loss, a new and concerning side effect is coming to light—what patients are informally calling “Ozempic teeth.”
This term, while not a clinical diagnosis, refers to a cluster of dental health issues increasingly reported by users of GLP-1 medications. These include tooth decay, heightened sensitivity, enamel erosion, gum inflammation, and in more severe cases, tooth loosening or loss.
Dr. Catrise Austin, DDS—a cosmetic dentist, author of Stop Diabetes Today, and host of the Let’s Talk Smiles Podcast—says that dental professionals are seeing a notable uptick in oral complications among patients taking GLP-1 drugs.
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“‘Ozempic teeth’ has become a catch-all phrase for these sudden and sometimes dramatic dental changes,” Austin told Healthline. “While anecdotal, these reports are growing as more individuals share their experiences online and in clinical settings.”
According to experts, several factors may contribute to these oral health issues, including dry mouth, frequent vomiting, and reduced appetite—all of which can impair normal saliva production and disrupt oral pH balance. These conditions make teeth more vulnerable to decay and damage.
The term joins a growing list of informal labels such as “Ozempic face” and “Ozempic butt,” which refer to the visible facial or body changes due to the rapid fat (and occasionally muscle) loss often associated with these medications. In the case of “Ozempic teeth,” however, the concern extends beyond appearance and into more serious health implications.
It’s important to note that this phenomenon is not exclusive to Ozempic. Other GLP-1 drugs—including tirzepatide (Mounjaro, Zepbound), liraglutide (Saxenda, Victoza), dulaglutide (Trulicity), and exenatide (Byetta, Bydureon BCise)—may also lead to similar side effects.
Given the potential risks, dental professionals strongly advise patients using GLP-1 medications to be diligent about oral hygiene, maintain regular dental checkups, and consult a healthcare provider if any new symptoms arise.
How Ozempic May Affect Your Dental Health
Dr. Catrise Austin, DDS, outlines several mechanisms by which GLP-1 medications like Ozempic may contribute to oral health issues. While not everyone will experience these effects, they are becoming increasingly common among users.
Dry Mouth (Xerostomia)
“Reduced salivary flow is one of the most common complaints I hear from patients on GLP-1 medications,” Austin explains. Saliva plays a crucial role in maintaining oral health—it neutralizes harmful acids, helps remineralize enamel, and washes away food particles and bacteria. Without adequate saliva, the risk of tooth decay, gum disease, and bad breath rises significantly.
Common symptoms of dry mouth include persistent thirst, difficulty swallowing, a sticky or tacky mouthfeel, and cracked or dry lips.
Nausea and Vomiting
According to clinical data from the U.S. Food and Drug Administration (FDA), nausea affects approximately 16% to 20% of Ozempic users, while 5% to 9% experience vomiting.
“Repeated vomiting exposes the teeth to stomach acid, which can wear down enamel and increase sensitivity,” says Austin. This type of erosion may lead to thinning, translucent teeth and heightened vulnerability to cavities.
Malnutrition and Nutrient Deficiencies
Appetite suppression—one of the intended effects of GLP-1 drugs for weight management—can sometimes result in reduced food intake to the point of nutritional deficiency.
“Deficiencies in essential nutrients such as vitamins C, D, and B-complex can impair gum health and slow healing,” Austin notes. These vitamins are vital for maintaining strong connective tissues, immune response, and healthy oral mucosa.
Neglected Oral Hygiene
When patients feel nauseated or fatigued, daily oral hygiene routines often fall by the wayside.
“Skipping brushing or flossing even for a few days can accelerate plaque buildup and contribute to rapid dental deterioration,” Austin warns.
For optimal oral care, experts recommend brushing twice a day and flossing at least once—ideally before brushing, to remove debris and maximize the effectiveness of fluoride toothpaste.
How to Protect Your Teeth While Using Ozempic
Dr. Ehsan Ali, MD—known as the “Beverly Hills Concierge Doctor” and a board-certified specialist in internal and geriatric medicine—echoes growing concern among healthcare providers about the dental side effects associated with GLP-1 medications like Ozempic. And, he emphasizes, the risks go beyond your smile.
“Oral health is deeply connected to overall health,” Ali told Healthline. “Poor dental hygiene can increase the risk of systemic infections, chronic inflammation, and even cardiovascular disease.”
Fortunately, there are several simple, evidence-based steps patients can take to protect their teeth and gums while using GLP-1 medications:
Prioritize Hydration
“Hydration is key,” says Ali. “Drink plenty of water throughout the day to combat dry mouth and maintain healthy saliva flow.”
You can also stimulate saliva production by chewing sugar-free gum or using a mouth rinse specifically formulated for dry mouth.
Maintain a Balanced Diet
While GLP-1 drugs often suppress appetite, it’s important not to skip meals. “Nutrients like calcium and vitamin D are essential for strong teeth and bones,” Ali explains.
Aim for a modest calorie deficit—typically 300 to 500 calories per day—if using the medication for weight loss, and ensure your diet includes key nutrients to support oral and overall health.
Excellent Oral Hygiene
Brush at least twice daily and floss once a day. Avoid sugary or acidic foods and beverages, which can accelerate enamel erosion and tooth decay—especially when dry mouth is present.
Neutralize Stomach Acid After Vomiting
For those experiencing nausea or vomiting, which are common side effects of GLP-1 drugs, Austin and Ali both advise rinsing the mouth with a mixture of water and baking soda before brushing. “This helps neutralize stomach acid and prevent enamel damage,” says Ali.
Avoid Dry Mouth Triggers
Dr. Austin adds that patients should limit substances known to worsen dry mouth, including alcohol, tobacco, and caffeine.
When to See a Dentist or Doctor About “Ozempic Teeth”
As the use of GLP-1 medications like Ozempic, Wegovy, and Mounjaro grows for managing diabetes and supporting weight loss, it’s essential to be aware of their potential impact on oral health.
Though “Ozempic teeth” isn’t a clinical diagnosis, the increasing number of patient reports involving dry mouth, enamel erosion, gum inflammation, and even tooth loss highlight a real and emerging concern.
Fortunately, simple preventive strategies—such as staying hydrated, practicing consistent oral hygiene, eating a nutrient-dense diet, and using products that support saliva production—can help reduce risk. But in some cases, professional care is necessary.
“If you’re noticing new tooth sensitivity, bleeding gums, persistent bad breath, or sudden changes like tooth breakage or looseness, it’s time to see your dentist,” advises Dr. Ehsan Ali, MD, a board-certified internal medicine physician.
Frequent nausea or vomiting—common side effects of GLP-1 drugs—can also cause lasting harm to your teeth. In these cases, Dr. Ali recommends contacting the prescribing physician.
“They may need to adjust your dosage or prescribe something to protect your stomach lining,” he explains. “The earlier we intervene, the easier it is to manage—and ideally, prevent—permanent damage.”
Being proactive and open with your healthcare providers can help you safely stay on track with your treatment goals while preserving your long-term oral health.
Frequently Asked Questions
What is “Ozempic teeth”?
“Ozempic teeth” is an informal term used by patients and healthcare providers to describe dental side effects associated with GLP-1 medications like Ozempic, Wegovy, and Mounjaro. Reported symptoms include dry mouth, enamel erosion, increased sensitivity, gum inflammation, and in severe cases, tooth loss.
Are these dental side effects officially recognized?
While “Ozempic teeth” is not a clinical diagnosis, the symptoms are real and increasingly reported. Dental professionals and physicians are taking note of these patterns, though more research is needed to establish a formal link.
Why do GLP-1 drugs affect oral health?
Possible contributing factors include dry mouth (reduced saliva), nausea and vomiting (exposure to stomach acid), appetite suppression (reduced nutrient intake), and lapses in oral hygiene due to medication side effects.
Is it just Ozempic causing this?
No. Other GLP-1 medications—including Wegovy, Mounjaro, Saxenda, Trulicity, and Victoza—may produce similar oral side effects.
When should I see a dentist or doctor?
If you experience any persistent dental changes, new oral symptoms, or frequent nausea/vomiting, consult your dentist and the doctor managing your GLP-1 prescription. Early intervention can help prevent more serious complications.
Should I stop taking my medication if I have dental issues?
Do not stop any prescribed medication without consulting your healthcare provider. They may adjust your dose, add a protective medication, or collaborate with your dentist to address side effects safely.
Conclusion
As GLP-1 medications like Ozempic, Wegovy, and Mounjaro continue to transform the landscape of diabetes and weight management, it’s important to recognize their potential impact beyond blood sugar and body weight—including on oral health.
While “Ozempic teeth” is not an official diagnosis, the growing number of reports linking these medications to dental issues such as dry mouth, enamel erosion, and tooth loss signals a need for greater awareness and proactive care.